Discover StiCol®
Volume & Soft

Collagen Stimulator to Restore Facial Volume Collagen Stimulation Skin Booster

Revitalize your skin with our Collagen Stimulator and Skin Booster, designed to restore facial volume and enhance skin elasticity. This innovative treatment promotes natural collagen production, leaving your skin looking youthful, plump, and radiant.

Own Natural Collagen Stimulator to Restore Its Inner Skin

• Microsphere PLLA
• Composited of Microsphere PLLA and HA
• Stimulates Own Skin to produce New Collagen as a Bio-Stimulatory Dermal Filler
• Restore Facial Volume
• Skin Booster for Skin Tightening, Lifting and Whitening
• FDA and CE Approved Biodegradable Polymer PLLA and HA

StiCol Volume

TypeVolumlized PLLA
Ingredient 356mg,PLLA 150mg / vial
Particle size±50 micron
Injection layer Subcutaneous layer
Indications Volume Booster(Facial wrinkles and folds)
Needle and cannula 21-25G cannula
Amount 10cc(saline water, lidocaine)

StiCol Soft

TypeMicronized PLLA
Ingredient 120mg / PLLA, 50mg / vial
Particle size±30 micron
Injection layerHypodermis layer
Indications Skin Booster
Needle and cannula 25-27G cannula
Amount 5cc(saline water, lidocaine)

SS-A

TypeSlightly Cross-linked HA
Concentration 1%
Weight 160 Dalton
Indication Additive
Amount 5.5 ml

StiCol® Volume & Soft

It is an injectable and biocompatible medical device and restores the volume lost by collagen lost due to age and tightens the skin. Injectable poly-L-lactic acid (PLLA) is a synthetic, biocompatible and biodegradable polymer device for correction of facial wrinkles and for restoration and correction of signs of facial fat loss.

Face Rejuvenation

  • Deep Dermal Deficiency
  • Face Wrinkles and Folds
  • Marrionette Line
  • Temple
  • Sagging Jowls
  • Scarring

Body Rejuvenation

  • Deep Dermal Deficiency
  • Face Wrinkles and Folds
  • Marrionette Line
  • Temple
  • Sagging Jowls
  • Scarring

Skin that feels like you again

Safety of PLLA

Injectable poly-L-lactic acid (PLLA) has been proven safe and effective with numerous medical applications for more than 25 years. It is a synthetic biocompatible, biodegradable and absorbable bio-stimulatory polymer and is being used for soft tissue augmentation in the face and certain body parts.
Its use of soft tissue augmentation to cosmetically correct wrinkles and scars were approved by Europe(CE) and FDA.

The morphology of its regular microsphere, smooth surface and the uniform of particle size greatly increases clinical results and its safety.

Superior Collagen Stimulator PLLA1)

Therefore, compared with PDLA MS and PDLLA MS, PLLA MS is a skin filling material with lower cost, lower side reaction, better filling effect and excellent collagen stimulating effect.
Furthermore, PLLA MS can contain collagen and other substances that are beneficial to skin repair and collagen regeneration, which can be released slowly through PLLA degradation to achieve better cosmetic effect In breif, PLLA MS is a valuable and superior dermal filler.

The morphology of its regular microsphere, smooth surface and the uniform of particle size greatly increases clinical results and its safety.

Histological analysis of collagen regeneration. (A) Masson staining and (B) Picrosirius red staining of the skin at the injection site of three kinds of PLA microsphere on Day 30. Type I collagen fibers are red or yellow, type III collagen fibers are green. 

The content of type I collagen in the PLLA group was still 84.7%, and type III collagen was 15.1%. Total of type I and type III collagen were 1.4 times than the collagen in the PDLA group, and 1.1 times than the collagen in the PDLLA group (Fig. 4C). Which showed that PLLA MS has the most obvious effect on stimulating collagen regeneration, and it is indeed suitable for usage as dermal filler in comparison with the other two chiralities.

Before & After Results

Explore images of real people who chose Sticol for natural-looking, long-lasting results.
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Mechanism of the Action

  • Injectable poly-l-lactic acid is used to create structure, framework, and volume to the face and body
  • PLLA is a safe and effective treatment for cosmetic enhancement by stimulating new collagen.
  • Once the carrier solution is reabsorbed, a slow process of biodegradation of the microspheres
    occurs consisting of hydration, loss of cohesion and molecular weight, solubilization, and
    phagocytosis of small fragments of PLLA by the host’s macrophages.
  • PLLA is eventually degraded into lactic acid which is eliminated as CO2 and H2O through the
    respiratory system.

PLLA Injection

Stimulation of Subclinical Inflammatory Response

Encapsulation of the particles

Fibroblast Proriferlation and Collagen Formation

Gradually Restore Volume and Tightening Skin

STEP 01

Inject diluted StiCol into the subcutaneous layer of the skin.

STEP 02

Firstly wrinkle improvement can be shown with WFI(Water for injection) and diluted StiCol.

STEP 03

Within some days, after absorbing water, only StiCol particles left.

STEP 04

New cells are gathered around PLLA and increasing fibroblasts.

STEP 05

Increased fibroblasts stimulate collagen generation and improve skin folds.

STEP 06

Generated collagen lasts for 2 years and StiCol particles are biodegraded.

How to Use

Reconstitution
Reconstitution can be performed the day before or on the day of the procedure depending on the situation

The day before the procedure On the day of the procedure
Protocol Add normal saline or HA Additive Solution(SS-A) 24 hours before the procedure. Shake gently for 10 minutes before use. Add normal saline or HA Additive Solution(SS-A) 24 hours before the procedure. Shake gently for 10 minutes before use.
Amount of Normal salineWe have a standard reconstitution guideline for each indication. But the amount of normal saline or HA Additive Solution(SS-A) may differ depending on the operator's preference.
Others When mixing anesthetics according to the operator's preference, 1 ml of normal saline can be removed and 1ml of lidocaine can be added.

StiCol®

Safe & Long lasting volumizing

Natural Collagen